Familial Dysautonomiais a genetic condition that impacts how certain types of nerve cells develop and survive. There are many other types of Dysautonomia including: (i) Postural Orthostatic Tachycardia Syndrome (POTS), (ii) Neurocardiogenic Syncope (NCS), the most common subtype, and (iii) Multiple System Atrophy (MSA). Many types of Dysautonomia share symptoms with each other, including lightheadedness and fainting, possibly caused by low blood pressure upon standing. POTS symptoms may include chest pain, exercise intolerance, and tachycardia, which is a heart rate that is faster than normal when resting. Additional symptoms of NCS are cluster headaches, feeling pins and needles and irregularities with sweating. MSA is the most severe form of Dysautonomia and can include migraines and being bedridden.
Some rare conditions, such as Charcot-Marie-Tooth Disease(CMT) and Ehlers-Danlos Syndrome (EDS), share several symptoms with certain forms of Dysautonomia. POTS shares several symptoms with Catecholaminergic polymorphic ventricular tachycardia (CPVT or CASQ2-CPVT). And, NCS shares symptoms with the rare genetic disorder Hereditary (familial) ATTR amyloidosis (hATTR).
Could my Dysautonomia symptoms have a genetic cause?
